| # | Player | Team | GP | G | A | P | +/- |
|---|---|---|---|---|---|---|---|
| 1 | Brett Kulak | EDM, PIT, COL | 83 | 1 | 11 | 12 | -4 |
| 2 | Wyatt Johnston | DAL | 82 | 45 | 41 | 86 | -5 |
| 3 | Jonas Siegenthaler | NJD | 82 | 0 | 16 | 16 | -9 |
| 4 | Pavel Dorofeyev |
| 82 |
| 37 |
| 27 |
| 64 |
| -3 |
| 5 | Darnell Nurse | EDM | 82 | 7 | 17 | 24 | -12 |
| 6 | Emil Heineman | NYI | 82 | 22 | 9 | 31 | -13 |
| 7 | Claude Giroux | OTT | 82 | 14 | 35 | 49 | 20 |
| 8 | Marcus Pettersson | VAN | 82 | 3 | 15 | 18 | -19 |
| 9 | Dylan DeMelo | WPG | 82 | 3 | 16 | 19 | 7 |
| 10 | Barclay Goodrow | SJS | 82 | 5 | 7 | 12 | -18 |
| 11 | Morgan Frost | CGY | 82 | 22 | 21 | 43 | -16 |
| 12 | Jackson LaCombe | ANA | 82 | 10 | 48 | 58 | -2 |
| 13 | Mattias Ekholm | EDM | 82 | 6 | 35 | 41 | 32 |
| 14 | Noah Cates | PHI | 82 | 18 | 29 | 47 | 26 |
| 15 | Brian Dumoulin | LAK | 82 | 2 | 15 | 17 | -1 |
| 16 | Nick Schmaltz | UTA | 82 | 33 | 41 | 74 | 17 |
| 17 | Brent Burns | COL | 82 | 12 | 23 | 35 | 33 |
| 18 | Ivan Provorov | CBJ | 82 | 9 | 22 | 31 | 14 |
| 19 | Brandt Clarke | LAK | 82 | 8 | 32 | 40 | 11 |
| 20 | Adam Larsson | SEA | 82 | 7 | 18 | 25 | 0 |
| 21 | Adam Pelech | NYI | 82 | 4 | 12 | 16 | 4 |
| 22 | John Tavares | TOR | 82 | 31 | 40 | 71 | -28 |
| 23 | Yanni Gourde | TBL | 82 | 9 | 19 | 28 | -6 |
| 24 | John-Jason Peterka | UTA | 82 | 25 | 22 | 47 | 6 |
| 25 | Charlie Coyle | CBJ | 82 | 20 | 38 | 58 | 3 |
| 26 | Ian Cole | UTA | 82 | 3 | 20 | 23 | 16 |
| 27 | Macklin Celebrini | SJS | 82 | 45 | 70 | 115 | 8 |
| 28 | Yakov Trenin | MIN | 82 | 6 | 17 | 23 | 13 |
| 29 | Braden Schneider | NYR | 82 | 2 | 16 | 18 | -5 |
| 30 | Sam Malinski | COL | 82 | 8 | 32 | 40 | 43 |
| 31 | Evan Bouchard | EDM | 82 | 21 | 74 | 95 | 25 |
| 32 | Joel Farabee | CGY | 82 | 20 | 18 | 38 | -9 |
| 33 | Jack Quinn | BUF | 82 | 20 | 31 | 51 | 4 |
| 34 | Anthony Beauvillier | WSH | 82 | 15 | 13 | 28 | 7 |
| 35 | Fraser Minten | BOS | 82 | 17 | 18 | 35 | 21 |
| 36 | Bowen Byram | BUF | 82 | 11 | 31 | 42 | 15 |
| 37 | Alex DeBrincat | DET | 82 | 41 | 44 | 85 | 8 |
| 38 | Brady Skjei | NSH | 82 | 3 | 23 | 26 | -7 |
| 39 | Joel Edmundson | LAK | 82 | 2 | 21 | 23 | 14 |
| 40 | Dylan Cozens | OTT | 82 | 28 | 31 | 59 | -7 |
| 41 | J.T. Compher | DET | 82 | 11 | 17 | 28 | -13 |
| 42 | Alex Killorn | ANA | 82 | 15 | 18 | 33 | -2 |
| 43 | Steven Stamkos | NSH | 82 | 42 | 24 | 66 | -17 |
| 44 | Cody Ceci | LAK | 82 | 1 | 8 | 9 | -10 |
| 45 | Connor McDavid | EDM | 82 | 48 | 90 | 138 | 17 |
| 46 | Josh Doan | BUF | 82 | 25 | 27 | 52 | -4 |
| 47 | Ryan Donato | CHI | 82 | 15 | 15 | 30 | -16 |
| 48 | Matt Savoie | EDM | 82 | 18 | 19 | 37 | 6 |
| 49 | Dmitry Orlov | SJS | 82 | 3 | 34 | 37 | -28 |
| 50 | Ivan Barbashev | VGK | 82 | 23 | 38 | 61 | 20 |